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| {{DiseaseDisorder infobox | | | {{Infobox Windows |
| Name = Genital wart|
| | |imagecaption = Windows Home Server |
| Image = SOA-Condylomata-acuminata-around-anus.jpg|
| | |codename = Quattro |
| Caption = Severe case of genital warts around the anus|
| | |kernel = NT 5.2 |
| ICD10 = {{ICD10|A|63|0|a|50}} |
| | |arch = x64 |
| ICD9 = {{ICD9|078.11}} |
| | |build = 6.0.3436 |
| ICDO = |
| | |release = 4th November 2007 |
| OMIM = |
| | |licence = Microsoft EULA |
| DiseasesDB = 29120 |
| | |support = 8th January 2013 |
| MedlinePlus = |
| | |previous = N/A |
| eMedicineSubj = derm |
| | |next = [[Windows Home Server 2011]] |
| eMedicineTopic = 454 |
| |
| eMedicine_mult = {{eMedicine2|med|1037}} |
| |
| MeshName = Genital+Warts |
| |
| MeshNumber = C02.256.650.810.217 |
| |
| }} | | }} |
| '''Genital warts''' (or '''[[Condyloma]] acuminata''', '''venereal warts''', '''anal warts''' and '''anogenital warts''') is a highly contagious [[sexually transmitted disease]] caused by some sub-types of [[human papillomavirus]] (HPV). It is spread through direct skin-to-skin contact during [[oral sex|oral]], [[genital]], or [[anal sex]] with an infected partner. [[Warts]] are the most easily recognized symptom of genital HPV infection. They can be caused by strains 6, 11, 30, 42, 43, 44, 45, 51, 52 and 54 of HPV; types 6 and 11 are responsible for 90% of genital warts cases.<ref name=eMed_1037>{{eMedicine|med|1037}}</ref> Less than 1% of those infected develop clinically obvious warts, but those infected can still transmit the virus,<ref name=CurrentManagement>{{cite journal |author=O'Mahony C |title=Genital warts: current and future management options |journal=Am J Clin Dermatol |volume=6 |issue=4 |pages=239–43 |year=2005 |pmid=16060711 |doi= |url=}}</ref> although another source states that 70% of those who have sexual contact with an infected partner develop genital warts.<ref name=OpenAccess2006/>{{Dubious|date=September 2009|probability of warts from infected partner}} Other types of HPV also cause [[cervical cancer]] and probably most [[anal cancer]]s. | | '''Windows Home Server''' is a "server for the home" solution by [[Microsoft]]. The core operating system is [[Windows Server 2003|Windows Small Business Server 2003]], and the Dashboard and an embedded website has been added to it. |
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| ==Signs and symptoms==
| | Users can log on remotely, can have personal file shares on the server, and can post images to the web using the embedded web site function (Remote Access). |
| Genital warts often occur in clusters and can be very tiny or can spread into large masses in the genital or penis area. In other cases they look like small stalks. In women they occur on the outside and inside of the [[vagina]], on the opening ([[cervix]]) to the womb ([[uterus]]), or around (or inside) the [[anus]]. They are approximately as prevalent in men but the symptoms may be less obvious. When present, they usually are seen on the tip of the [[penis]]. They also may be found on the shaft of the penis, on the [[scrotum]], or around (or inside) the [[anus]]. Rarely, genital warts also can develop in the mouth or throat of a person who has had oral sex with an infected person.
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| The viral particles are able to penetrate the skin and mucosal surfaces through microscopic abrasions in the genital area, which occur during sexual activity. Once cells are invaded by HPV, a latency (quiet) period of months to years (decades) may occur. HPV can last for several years without a symptom.<ref>{{cite web |url=http://www.cancer.org/docroot/CRI/content/CRI_2_2_2x_Can_Anal_Cancer_Be_Prevented.asp?sitearea=|title=American Cancer Society: "Can Anal Cancer Be Prevented?"|accessdate=2008-09-10}}</ref> Having sex with a partner whose HPV infection is latent and demonstrates no outward symptoms still leaves one vulnerable to becoming infected. If an individual has unprotected sex with an infected partner, there is a 70% chance that he or she will also become infected. The [[immune system]] eventually clears the virus through [[interleukin]]s, which recruit [[interferon]]s, which slow viral replication.<ref name=ModernManagement/>
| | == Motivation == |
| | A blog post on TechNet says that they "thought long and hard about what we should call the product": |
| | {{quotation|In the 1960s & 70s the idea of a home computer was unheard of outside of science fiction circles. Before the late 1980s home networks were unheard of. |
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| <gallery>
| | In 1975 Microsoft was founded with the vision of putting "A computer on every desk and in every home...". Microsoft led the charge in creating a world where a "home computer" something you expect to see in a home. |
| Image:SOA-Condylomata-acuminata-female.jpg|Severe case of genital warts on a female
| | By including great support for networking technologies (particularly TCP/IP) in Windows 3x and 95 Microsoft ensured ubiquitous networking in businesses and homes. Today there are over 100 million households with a "home network" and Microsoft led the world in making this happen. |
| Image:SOA-Condylomata-acuminata-man.jpg|Severe case of genital warts on a male
| |
| </gallery>
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| ==Vaccines==
| | When we set about building Windows Home Server we knew we were going to be defining a new category of products and solutions for consumers. We thought long and hard about what we should call the product. As you would expect, there was no shortage of opinions. In fact some very, very senior executives at Microsoft were quite forceful in saying "whatever you do, don't call it a server". |
| {{Seealso | HPV vaccine}}
| | So we worked hard at trying to come up with another name. We tried other "descriptive" names such as "hub". We tried fanciful names (like "Poodle"). But at the end of the day we recognized that no matter what we called the product we would always be describing it as a home server, because that's what it is: A device on a home network that provides centralized services over the network to other devices – helping consumers protect, organize and share their digital content. |
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| [[Gardasil]] (sold by [[Merck & Co.]]) is a [[vaccine]] that protects against [[human papillomavirus]] types 16, 18, 6, and 11. Types 6 and 11 cause genital warts, while 16 and 18 cause [[cervical cancer]]. The vaccine is preventive, not therapeutic, and must be given before exposure to the virus type to be effective, ideally before the beginning of sexual activity. The vaccine is widely approved for use by young women, it is being tested for young men,<ref name="Bloomberg">[http://www.bloomberg.com/apps/news?pid=20601202&sid=aajzweDaXZh0&refer=healthcare Cortez, Michelle Fay and Pettypiece, Shannon. "Merck Cancer Shot Cuts Genital Warts, Lesions in Men". ''Bloomberg News''. (Bloomberg.com) 13 Nov 2008.]</ref><ref> [http://www.webmd.com/sexual-conditions/hpv-genital-warts/news/20081113/hpv-vaccine-gardasil-may-help-boys-men HPV Vaccine Gardasil May Help Boys, Men] by WebMD Health News, Nov 13, 2008</ref> and has been approved for males in some areas, such as the UK.
| | In addition, as we did our research we discovered some very interesting things. First, we found that the only people who didn't like the term "server" were technical people who thought they understood consumers. Then we discovered that consumers in our target market (consumers who already have a home network and multiple PCs) understood what a server is, loved the name and the concept, and thought it was "the inevitable next step". In fact we heard loud and clear that many such consumers would feel proud to be able to say they had a server in their home. |
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| ==Management==
| | This week we started an online advertising campaign for Windows Home Server that, in a humorous way will help explain how Windows Home Server can help families. The campaign complements a range of other communications efforts including events, webinars, online and in-store demonstrations and more. |
| There is no cure for HPV, but there are methods to treat visible warts, which could reduce infectivity, although there are no trials studying the effectiveness of removing visible warts in reducing transmission.<ref name=FamilyManagement/> Genital warts may disappear without treatment, but sometimes eventually develop a fleshy, small raised growth. There is no way to predict whether they will grow or disappear. Warts can sometimes be identified because they show up as white when [[acetic acid]] is applied, but this method is not recommended on the vulva because microtrauma and inflammation can also show up as acetowhite.<ref name=ModernManagement/> Magnifying glasses or colposcope may also be used to aid in identifying small warts.<ref name=ModernManagement/>
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| Depending on the sizes and locations of warts (as well as other factors), a doctor will offer one of several ways to treat them. Podofilox is the first-line treatment due to its low cost.<ref>{{cite journal |author=Fox PA, Tung MY |title=Human papillomavirus: burden of illness and treatment cost considerations |journal=Am J Clin Dermatol |volume=6 |issue=6 |pages=365–81 |year=2005 |pmid=16343025 |doi= |url=}}</ref> Almost all treatments can potentially cause depigmentation or scarring.<ref name=FamilyManagement>{{cite journal |author=Kodner CM, Nasraty S |title=Management of genital warts |journal=Am Fam Physician |volume=70 |issue=12 |pages=2335–42 |year=2004 |month=December |pmid=15617297 |doi= |url=http://www.aafp.org/afp/20041215/2335.html}}</ref>
| | This campaign will drive home (pun intended) the idea that just as Microsoft was the leader in making "home computer" and "home network" common household terms it is doing it again for "home server". |
| | You can find the landing site for the campaign at www.stayathomeserver.com. Over the next few weeks we will roll out more funny video vignettes that will help families understand why they should have a home server in their household. |
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| | We've also commissioned a funny fake children's book titled "Mommy, Why is there a Server in my House?" which will help parents explain why there is a new member of the family. We are sure the book will become a best seller! Check out a teaser of the book on [http://web.archive.org/web/20080405153902/http://www.stayathomeserver.com/ www.stayathomeserver.com] right now. |
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| * A 0.15% – 0.5% [[podophyllotoxin]] (also called podofilox) solution in a gel or cream. Marketed as Condylox (0.5%), Wartec (0.15%) and Warticon (0.15%),<ref name=AbandonPodophyllin/> it can be applied by the patient to the affected area and is not washed off. It is the purified and standardized active ingredient of the podophyllin (see below). Podofilox is safer and more effective than podophyllin.<ref name=AbandonPodophyllin/> Skin erosion and pain are more commonly reported than with imiquimod and sinecatechins.<ref name=GreenTea/> Its use is cycled (2 times per day for 3 days then 4–7 days off); one review states that it should only be used for four cycles.<ref name=OpenAccess2006/>
| | We have home computers, home networks, and the era of home servers has just begun...|"cek"|<ref>https://blogs.technet.microsoft.com/homeserver/2007/11/30/home-computer-home-network-home-server/</ref>}} |
| * [[Imiquimod]] (Aldara) is a topical immune response cream, applied to the affected area. It causes less local irritation than podofilox but may cause fungal infections (11% in package insert) and flu-like symptoms (less than 5% disclosed in package insert).<ref name=GreenTea/>
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| *Sinecatechins (marked as Veregen and Polyphenon E) is an ointment of catechins (55% [[epigallocatechin gallate]]<ref name=ModernManagement/>) extracted from [[green tea]] and other components. Mode of action is undetermined.<ref>{{cite web | url=http://www.veregenrx.com/IL331%20Veregen%20PI%20170mm_x_420mm.pdf|format=PDF|title=Veragen package insert|accessdate=2008-08-18}}</ref> It appears to have higher clearance rates than podofilox and imiquimod and causes less local irritation, but clearance takes around longer than imiquimod and sinecatechins.<ref name=GreenTea>{{cite journal |author=Meltzer SM, Monk BJ, Tewari KS |title=Green tea catechins for treatment of external genital warts |journal=Am. J. Obstet. Gynecol. |volume=200 |issue=3 |pages=233.e1–7 |year=2009 |month=March |pmid=19019336 |doi=10.1016/j.ajog.2008.07.064 |url=}}</ref>
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| * [[Liquid nitrogen]] [[cryosurgery]] is safe for pregnancy. It kills warts 71–79% of the time, but recurrence is 38% to 73% 6 months after treatment.<ref name=ModernManagement/> Local infections have been reported.<ref name=ModernManagement/>
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| * [[Trichloroacetic acid]] (TCA) is less effective than [[cryosurgery]],<ref name=OpenAccess2006/> and is not recommended for use in the vagina, cervix, or urinary meatus.<ref name=ModernManagement/>
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| * Surgical excision is best for large warts, and has a greater risk of scarring.<ref name=FamilyManagement/>
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| * Laser [[ablation]] does not seem to be any more effective than other physician-applied methods,<ref name=CurrentManagement/> but is often used as a last resort and is extremely expensive.<ref name=ModernManagement/>
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| * A 20% [[podophyllin]] anti-[[mitosis|mitotic]] solution , applied to the affected area and later washed off. However, this crude herbal extract is not recommended for use on vagina, urethra, perianal area, or cervix,<ref name=ModernManagement/> and must be applied by a physician.<ref name=AbandonPodophyllin>{{cite journal |author=von Krogh G, Longstaff E |title=Podophyllin office therapy against condyloma should be abandoned |journal=Sex Transm Infect |volume=77 |issue=6 |pages=409–12 |year=2001 |month=December |pmid=11714936 |pmc=1744412 |doi=10.1136/sti.77.6.409 |url=http://sti.bmj.com/cgi/content/full/77/6/409}}</ref> Reported reactions include nausea, vomiting, fever, confusion, coma, renal failure, ileus, and leukopenia; death has been reported with extensive topical application, or application on mucous membranes.<ref name=ModernManagement/>
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| * [[Interferon]] can be used; it is effective, but it is also expensive and its effect is inconsistent.<ref name=OpenAccess2006/>
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| * [[Electrocauterization]] can be used; it is an older procedure but recovery time is generally longer. In severe cases of genital warts,treatment may require general or spinal anesthesia. This is a surgical procedure. More effective than [[cryosurgery]] and recurrence is at a much lower rate.
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| ;Discontinued:
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| * A 5% 5-[[fluorouracil]] (5-FU) cream was used, but it is no longer considered an acceptable treatment due to the side-effects.<ref name=ModernManagement>{{cite journal |author=Mayeaux EJ, Dunton C |title=Modern management of external genital warts |journal=J Low Genit Tract Dis |volume=12 |issue=3 |pages=185–92 |year=2008 |month=July |pmid=18596459 |doi=10.1097/LGT.0b013e31815dd4b4 |url=}}</ref>
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| Podophyllin and podofilox should not be used during [[pregnancy]], as they are absorbed by the skin and could cause [[birth defect]]s in the [[fetus]].
| | == [[:File:Mommy, Why is There a Server in the House.pdf|Mommy, Why is There a Server in the House?]] == |
| | Along with the launch of Windows Home Server, a book was released for publicity: [[:File:Mommy, Why is There a Server in the House.pdf|Mommy, Why is There a Server in the House?]]. The description for the book read like this: |
| | {{quote|A "stay-at-home" server: you know it's the right thing for your family. But how do you explain this wonderful choice to your children? Finally, there's a book that talks about the home server using small words and fun pictures, perfect for kids. Written by Tom O'Connor and lovingly illustrated by Jill Dublin, this is a book you and your family will want to read over and over again.|<ref>https://www.amazon.com/Mommy-Why-There-Server-House/dp/160530641X</ref>}} |
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| ==Epidemiology==
| | However, "Tom O'Connor" was not a real person, and the book made this clear in its introduction. |
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| Genital HPV infections have an estimated prevalence in the US of 10–20% and clinical manifestations in 1% of the sexually active adult population.<ref name=OpenAccess2006/> Incidence of HPV infection has increased between 1975 and 2006.{{where|date=September 2009}}<ref name=OpenAccess2006/> About 80% of those infected are between the ages of 17–33.<ref name=OpenAccess2006/> Although treatments can remove the warts, they do not remove the HPV, so warts can recur after treatment (about 50–73% of the time<ref name=CDC2004>CDC. (2004). [http://www.cdc.gov/std/HPV/2004HPV%20report.pdf REPORT TO CONGRESS: Prevention of Genital Human Papillomavirus Infection].</ref>), and also spontaneously regress.<ref name=OpenAccess2006/> Traditional theories postulated that the virus remained in the body for a lifetime. However, new studies using sensitive DNA techniques have shown that through immunological response the virus can either be cleared or suppressed to levels below what [[polymerase chain reaction]] (PCR) tests can measure. One study testing genital skin for subclinical HPV using PCR found a prevalence of 10%.<ref name=OpenAccess2006>{{cite journal |author=Scheinfeld N, Lehman DS |title=An evidence-based review of medical and surgical treatments of genital warts |journal=Dermatol. Online J. |volume=12 |issue=3 |pages=5 |year=2006 |pmid=16638419 |doi= |url=http://dermatology.cdlib.org/123/reviews/warts/scheinfeld.html}}</ref>
| | A MSDN blog post covered the launch of the book, saying that: |
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| == See also ==
| | {{quote|The team also has a new book out, just in time for the holidays and to help parents answer some of the most difficult questions that parents have to confront... namely that new piece of hardware connected to the home network. <br> |
| * [[List of cutaneous conditions]]
| | Forget about explaining about the birds and the bees, "Mommy, Why is there a Server in my House?" will help parents explain why there is a new member of the family. You can find more info on this new book on [http://web.archive.org/web/20080405153902/http://www.stayathomeserver.com/ www.stayathomeserver.com] today, and coming to a major e-tailer near you.|"M3 Sweatt"|<ref>https://blogs.msdn.microsoft.com/mthree/2007/12/05/mommy-why-is-there-a-server-in-my-house/</ref>}} |
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| ==References== | | == Builds == |
| {{Reflist}} | | {{Builds Legend}} |
| | ===Beta 1=== |
| | *'''[[Windows Home Server/6.0.1282|6.0.1282]]''' |
| | ===Beta 2=== |
| | *'''''[[Windows Home Server/6.0.1301.qhsv1 main.070117-1800|6.0.1301.qhsv1_main.070117-1800]]''''' |
| | ===Community Technology Preview=== |
| | *'''''[[Windows Home Server/6.0.1371.qhsv1 main.070410-0000|6.0.1371.qhsv1_main.070410-0000]]''''' |
| | ===Release Candidate=== |
| | *'''''[[Windows Home Server/6.0.1424.2.qhsv1 rc.070606-1800|6.0.1424.2.qhsv1_rc.070606-1800]]''''' |
| | ===RTM=== |
| | *'''''[[Windows Home Server/6.0.1500.6.qhsv1 rtm qfe.070906-1800|6.0.1500.6.qhsv1_rtm_qfe.070906-1800]]''''' |
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| ==External links== | | == References == |
| * The ''SexInfo'' website run by students at the [[University of California at Santa Barbara]] has articles on both [http://www.soc.ucsb.edu/sexinfo/article/anal-warts Anal Warts] and [http://www.soc.ucsb.edu/sexinfo/article/genital-warts Genital Warts]
| | <references /> |
| * [http://search.dmoz.org/cgi-bin/search?search=Genital+warts Genital warts] at the [[Open Directory Project]]
| |
| * [http://www.cdc.gov/std/hpv/default.htm HPV information from the US CDC]
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| * [http://www.cdc.gov/std/HPV/2004HPV%20Report.pdf CDC Report to Congress]
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| * [http://dermatology.cdlib.org/123/reviews/warts/scheinfeld.html An evidence-based review of medical and surgical treatments of genital warts.] Noah Scheinfeld and Daniel S Lehman. [[Dermatology Online Journal]] (2006) 12 (3): 5.
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| <!--spacing, please do not remove-->
| | [[Category:Microsoft Windows]] |
| | |
| {{STD/STI}}
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| {{Viral diseases}}
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| {{Human papillomavirus}}
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| {{DEFAULTSORT:Genital Wart}}
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| [[Category:Infections with a predominantly sexual mode of transmission]]
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| [[Category:Papillomavirus]]
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| [[Category:Viral diseases]]
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| [[Category:Virus-related cutaneous conditions]] | |
Windows Home Server
 |
| Windows Home Server |
Codename
Preliminary name |
Quattro |
| Kernel version |
NT 5.2 |
| CPU architecture |
x64 |
| Release date |
4th November 2007 |
| Support end |
8th January 2013 |
| Preceded by |
N/A |
| Succeeded by |
Windows Home Server 2011 |
Windows Home Server is a "server for the home" solution by Microsoft. The core operating system is Windows Small Business Server 2003, and the Dashboard and an embedded website has been added to it.
Users can log on remotely, can have personal file shares on the server, and can post images to the web using the embedded web site function (Remote Access).
Motivation
A blog post on TechNet says that they "thought long and hard about what we should call the product":
In the 1960s & 70s the idea of a home computer was unheard of outside of science fiction circles. Before the late 1980s home networks were unheard of.
In 1975 Microsoft was founded with the vision of putting "A computer on every desk and in every home...". Microsoft led the charge in creating a world where a "home computer" something you expect to see in a home.
By including great support for networking technologies (particularly TCP/IP) in Windows 3x and 95 Microsoft ensured ubiquitous networking in businesses and homes. Today there are over 100 million households with a "home network" and Microsoft led the world in making this happen.
When we set about building Windows Home Server we knew we were going to be defining a new category of products and solutions for consumers. We thought long and hard about what we should call the product. As you would expect, there was no shortage of opinions. In fact some very, very senior executives at Microsoft were quite forceful in saying "whatever you do, don't call it a server".
So we worked hard at trying to come up with another name. We tried other "descriptive" names such as "hub". We tried fanciful names (like "Poodle"). But at the end of the day we recognized that no matter what we called the product we would always be describing it as a home server, because that's what it is: A device on a home network that provides centralized services over the network to other devices – helping consumers protect, organize and share their digital content.
In addition, as we did our research we discovered some very interesting things. First, we found that the only people who didn't like the term "server" were technical people who thought they understood consumers. Then we discovered that consumers in our target market (consumers who already have a home network and multiple PCs) understood what a server is, loved the name and the concept, and thought it was "the inevitable next step". In fact we heard loud and clear that many such consumers would feel proud to be able to say they had a server in their home.
This week we started an online advertising campaign for Windows Home Server that, in a humorous way will help explain how Windows Home Server can help families. The campaign complements a range of other communications efforts including events, webinars, online and in-store demonstrations and more.
This campaign will drive home (pun intended) the idea that just as Microsoft was the leader in making "home computer" and "home network" common household terms it is doing it again for "home server".
You can find the landing site for the campaign at www.stayathomeserver.com. Over the next few weeks we will roll out more funny video vignettes that will help families understand why they should have a home server in their household.
We've also commissioned a funny fake children's book titled "Mommy, Why is there a Server in my House?" which will help parents explain why there is a new member of the family. We are sure the book will become a best seller! Check out a teaser of the book on www.stayathomeserver.com right now.
We have home computers, home networks, and the era of home servers has just begun...
— "cek", [1]
Along with the launch of Windows Home Server, a book was released for publicity: Mommy, Why is There a Server in the House?. The description for the book read like this:
A "stay-at-home" server: you know it's the right thing for your family. But how do you explain this wonderful choice to your children? Finally, there's a book that talks about the home server using small words and fun pictures, perfect for kids. Written by Tom O'Connor and lovingly illustrated by Jill Dublin, this is a book you and your family will want to read over and over again.
However, "Tom O'Connor" was not a real person, and the book made this clear in its introduction.
A MSDN blog post covered the launch of the book, saying that:
The team also has a new book out, just in time for the holidays and to help parents answer some of the most difficult questions that parents have to confront... namely that new piece of hardware connected to the home network.
Forget about explaining about the birds and the bees, "Mommy, Why is there a Server in my House?" will help parents explain why there is a new member of the family. You can find more info on this new book on
www.stayathomeserver.com today, and coming to a major e-tailer near you.
Builds
- No information available
- Existence doubtful
- Information or pictures available
- Leaked or released
Beta 1
Beta 2
Release Candidate
RTM
References
