These disks came with a bundle of MS OS/2 SDKs. They are not original but backup copies.
The handwritten labels read:
OS/2 1.21.187 (GB)
Version 1 Level 00
VOL ID: OS/2 INSTALL (etc)
PRE-RELEASE
Checking the OSO001.MSG file on the Install disk identifies these as using the Microsoft OS/2 v1.21 command interpreter.
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